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Magnolia officinalis extract (igoa Igilisi: Magnolia officinalis PE ), mea aoga: ma magnolol, magnolol, magnolol total phenol. Punaoa fa'aola: O mea aoga i gaioiga fa'ama'i i le pa'u o Magnolia officinalis Rehder et Wilson, o se vaila'au fa'aSaina masani.

O lenei oloa o se tioata pa'epa'e pa'epa'e. Soluble i benzene, eter, chloroform, acetone, e le mafai ona solu i le vai, faigofie soluble i dilute alkali solution e maua ai le masima sodium. O le phenolic hydroxyl group e faigofie ona faʻamaʻiina, aʻo le vaega allyl e faigofie ona maua le tali faʻaopoopo.

E i ai se fa'apitoa fa'apitoa, fa'amama le fa'amalieina o maso ma le malosi o le antibacterial, lea e mafai ona fa'alavelaveina le fa'aputuga o platelet.

Clinically, e masani ona faʻaaogaina e avea o se vailaʻau antibacterial ma antifungal. O lenei oloa e tatau ona faʻamaufaʻailogaina mai le malamalama ma teu i totonu o se siosiomaga mago, malulu ma faʻaleleia lelei.

Le aoga ma le matafaioi a Magnolia Cortex Extract 2% Honokiol： 

Anti-inflammatory

I le faʻalavelave faʻafefe, o le cell membrane phospholipids e tuʻuina atu le arachidonic acid (AA) i lalo o le gaioiga a le phospholipase A2.

E lua auala metabolic mo AA, o le tasi o le gaosia o prostaglandins ma thromboxanes e ala i le gaioiga o le cyclooxygenase (COX), ma le isi o le gaosia o prostaglandins ma thromboxanes e ala i le gaioiga o le cyclooxygenase (COX). Ole gaioiga ole lipoxygenase (LO) e maua ai leukotrienes (LT).

Honokiol i maualuga maualuga na taofia ai le gaioiga o le COX i sela faʻalavelave, aʻo faʻalavelaveina le ala metabolic LO. O le mea lea, o le honokiol o se inhibitor lua o COX ma LO.

Ole a'afiaga ole fa'ama'i ole honokiol e mafai ona feso'ota'i ma lona fa'alavelaveina o auala fa'ama'i e lua ole AA. E le gata i lea, o le honokiol e mafai ona taofia le tuʻuina atu o enzymes lysosomal, faʻaitiitia le faʻaogaina o puipui o capillary i tafatafa o le nofoaga o le mumū, ma faʻalavelave le femalagaiga o leukocyte ma le faʻateleina o le fibrous tissue.

Antioxidant

O le Magnolol ma le Honokiol o loʻo i ai aʻafiaga faʻafefe faʻamalosi saoloto, lea e mafai ona faʻafefe ai faʻamaʻi parahydroxyl ma hydrogen peroxide.

I le taimi lava e tasi, e mafai ona puipuia le gaioiga a le mitochondrial respiratory chain enzymes e faasaga i le NADPH-induced peroxidative stress, faʻafefe le oxidative hemolysis o sela mumu toto, ma taofia le lipid peroxidation.

O le tele o suʻesuʻega in vitro ma in vivo na suʻesuʻeina le gaioiga o le antioxidant o le Magnolia officinalis extract, lea e 1000 taimi sili atu le malosi nai lo le alpha-tocopherol.