Flubendazole | 31430-15-6
Fa'amatalaga o oloa:
Flubenzimidazole o se vailaʻau faʻamaʻi faʻamaʻi benzimidazole e mafai ona faʻalavelaveina le faʻaogaina o nematode ma le faʻapipiʻiina o microtubules intracellular.
E mafai ona i ai se sootaga malosi ma le tubulin (le dimer subunit porotini o microtubules) ma taofia microtubules mai polymerizing i sela absorption (ie sela absorption i sela intestinal o nematodes). E mafai ona faʻamaonia e ala i le mou atu (lelei) cytoplasmic microtubules ma le faʻaputuina o vaega faalilolilo i totonu o le cytoplasm ona o le polokaina o felauaiga.
O le iʻuga, o le paʻu o le sela o le sela e sili atu ona manifinifi, ma faʻavaivaia le mafai ona eli ma mitiia meaʻai. Ona o le faʻaputuina o mea lilo (hydrolases ma proteolytic enzymes), e maua ai le lysis ma le faʻaleagaina o sela, ma iu ai ina oʻo atu i le oti parasite.
Talosaga:
O le Flubenzimidazole o se fa'ama'i fa'ama'i iniseti lautele e mafai ona togafitia lelei fa'ama'i i maile, e pei ole gastrointestinal roundworms, hookworms, ma whipworms; I le taimi lava e tasi, e mafai foi ona togafitia le tele o gastrointestinal parasites i puaa ma moa, e pei o Ascaris suum, Hyostrongylus rubidus, Oesophagostomum dentatum, Trichuris suis, Metastrongylus apri, ma isi.
Flubenzimidazole e le gata e mafai ona fasiotia tagata matutua ae faʻapea foʻi fuamoa.
